Cancer of the stomach and esophagus

Chinese experts announced that they have identified genetic mutations that appear in connection with cancer of the stomach and esophagus.

This discovery increases understanding of the origin of these two types of cancer and perhaps the possibility of a new therapeutic approach to these diseases.

Experts Sinsjeng University in Henan province, have analyzed the genes of 9053 people with esophageal cancer and 2766 patients with gastric cancer. In all patients consistently have occurred two mutations - PLCE1 location C20orf54 10q23 and 20p13 on the site.

It is obvious that these two mutations significantly contribute to the risk of cancer of the esophagus and stomach cancer among members of the majority Han Chinese people, as well as members of the Uighur-Kazakh population, the conclusion is a Chinese team, which managed the Li-Wang Dung.

In China, approximately half of the world register of cases of these two types of cancer. Stomach cancer is the second biggest killer among cancers, after lung cancer. Of it per year 803,000 people die worldwide from cancer of the esophagus and 400 000 people.

These two cancers are particularly common in those parts of China which consumes a lot of canned and salty foods, while eating less fruit and vegetables.

In the American study, conducted at the National Cancer Institute in Betesdi, a team of experts under the leadership of Christian Abneta is analyzing the DNA 2240 ethnic Chinese patients with gastric cancer and 2115 patients with esophageal cancer, found a constant occurrence of gene mutations PLCE1.